P0301 on Honda vehicles
82 owner complaints filed with NHTSA about Honda vehicles mention P0301 (Cylinder 1 Misfire Detected) - across 7 models. Below is where it shows up, by model and year.
Can you drive with it? Minimize driving; a flashing check engine light means stop - persistent single-cylinder misfire dumps raw fuel into the exhaust.
Symptoms, likely causes in order and realistic repair costs are on the main P0301 page - they do not differ much by brand. This page shows what is specific to Honda: which models and years actually report it.
Honda models reporting P0301
The number next to each year is how many NHTSA complaints for that car mention P0301. Owners rarely quote trouble codes when complaining, so real occurrence is many times higher - use these numbers to compare years, not as totals.
What Honda owners report
“vehicle may experience driveability issues, which may result in DTCs P0300 (random misfire detected), P0301 (No. 1 cylinder misfire detected), P0302 (No. 2 cylinder misfire detected), P0303 (No. 3 cylinder misfire detected), P0304 (No. 4 cylinder misfire detected), or P0172 (fuel system too rich) or a whirling noise coming from the engine compartment. POSSIBLE CAUSE Based on certain driving patterns and environmental factors, the DTC's stated above may be set or a whirling noise may occur. Apparently only certain vin numbers were affected, mine is not in the list but im still having the exact same issues.”2017 Honda CR-V · Aug 2026
“Our 2015 Honda Odyssey van has bad piston rings 1-3. The check engine light and all of the lights are on in the vehicle is not driving and idling poorly.This is the second time it has happened. The first time was under warranty at 112,000 miles, and now the van has 179,000 miles. There seems to be several recalls and known problems and warranty was extended last year, but we just missed it. The code is P0301. I took it to the Honda service and the spark plugs are fouled.”2015 Honda Odyssey · Apr 2026
P0301 on other makes
Makes with enough NHTSA reports of P0301 for their own page.
Counts are NHTSA owner complaints whose text mentions P0301 - owner-reported and unverified. Always confirm with a diagnosis of your specific vehicle.