2021 Ford E-350: problems, recalls and reliability
6 recalls and 20 owner complaints on record; most reports concern engine.
Data updated weekly · latest recall Nov 2025
All counts are reports filed with NHTSA in the United States - US market only, not worldwide totals.
Common problems
Computed from 20 owner complaints filed with NHTSA for this exact model year.
“Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Authority , Fitchburg MA 01420”Owner report · Engine · Mar 2025
“This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.”Owner report · Engine · Jul 2024
“This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.”Owner report · Engine · Jun 2024
Show 4 more owner reports
“This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.”Owner report · Engine · Apr 2024
“The contact owns a 2021 Ford E-350. The contact stated that while driving at undisclosed speeds, the power steering and brakes became inoperable. There were no warning lights illuminated. The vehicle was towed to the local dealer where it was diagnosed with loosened brake line fittings and an unknown fluid leak. The vehicle was repaired. The contact stated the failure was related to NHTSA Campaign Number: 22V013000 (Fuel System, Diesel). The manufacturer was contacted but no additional assistance was provided. The failure mileage was approximately 13,667.”Owner report · Steering · Jun 2022
“The contact owns a 2021 Ford E-350. The contact stated while driving 60 mph, the contact started to smell a burning odor coming from the RV. The contact attempted to pull over the RV to the side of the roadway however, the RV became difficult to steer. The contact pulled over the RV and checked underneath the RV and the front hood and noticed that power steering fluid had leaked all over the engine. The contact continued driving to his destination and then had the RV towed to an RV lot. The RV was not diagnosed nor repaired. The manufacturer was made aware of the failure. The failure mileage was approximate 5,000.”Owner report · Steering · Jul 2021
“The contact owns a 2021 Ford E-350. The contact stated while driving at various speeds in windy conditions, the "Service Advance-trac" warning message was displayed on the instrument panel. Soon after the initial message was displayed, the Traction Control, Pre-Collision Assist, Cruise Control, and the Hill Start Assist messages also all appeared on the instrument panel. The contact called and made an appointment with the local dealer however, the vehicle was not yet diagnosed nor repaired. The manufacturer had yet to be notified of the failure. The failure mileage was approximately 1,500.”Owner report · Forward Collision Avoidance · Jun 2021
When filing, owners marked a crash in 1 of these complaints and injuries in 0 - self-reported to NHTSA, not verified accident statistics.
Recalls - 6 campaigns
Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles that received an incomplete software update under recall 20V795. The engine cover may become excessively hot.
Remedy: Dealers will update the powertrain calibration for heat management under elevated idle conditions, free of charge. Owner notification letters were mailed January 7, 2026. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 25SC7. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning December 22, 2025.
Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. A wire harness in the rear of the vehicle may contact the vehicle frame, resulting in damage to the circuits that support the fuel pump and the anti-lock braking system (ABS).
Remedy: Ford will notify owners, and dealers will inspect the wire harness for damage. If no damage is found, dealers will apply anti-abrasion tape over the area and ensure clearance to surrounding components. If damage is found, dealers will splice in new wire and apply anti-abrasion tape over the area and ensure clearance to surrounding components. All services will be performed free of charge. The recall began May 18, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S13.
Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake hydroboost unit may result in a sudden loss of power steering fluid.
Remedy: Dealers will replace the power steering pressure line and the hydroboost jumper line, free of charge. Vehicles in this recall were previously recalled under 22V-089 and owners will need to have the new remedy completed even if their vehicle was remedied under the prior recall. Owner notification letters were mailed on June 21, 2024. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 24S07.
Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake Hydroboost unit may result in a sudden loss of power steering fluid.
Remedy: Dealers will inspect the connection between the power steering lines and the Hydroboost unit, and replace the power steering lines, as necessary, free of charge. Owner notification letters were mailed on March 18, 2022. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 22S08.
Ford Motor Company (Ford) is recalling certain 2020 F-550 and 2021 E-350 and E-450 vehicles. The rear axle differential fluid may be below the minimum level, possibly resulting in a failure of the rear axle assembly and driveshaft separation.
Remedy: Ford will notify owners, and dealers will inspect the rear axle differential fluid level and adjust it, or replace the rear axle as necessary, free of charge. The recall began March 19, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S09.
Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. The underside of the engine cover may have mispositioned insulation, allowing the cover to get excessively hot.
Remedy: Ford will notify owners, and dealers will inspect the engine cover for gaps between the rubber seal and the insulation. If gaps are present, the dealer will install engine cover insulation patches in the right hand and left hand inner lower corners of the engine cover. The dealer will also update the powertrain calibration for heat management under elevated idle conditions should a vehicle be equipped with SEIC or BCP, free of charge. The recall began February 15, 2021. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S73.
Specifications
Factory options offered for the 2021 model year, decoded from the NHTSA vPIC database. Individual vehicles have one of each.
How other years compare
Check your exact E-350 by VIN
Recalls and equipment differ between individual vehicles. Decode your VIN to see what applies to yours.
Open VIN decoderFrequently asked questions
Is the 2021 Ford E-350 reliable?
NHTSA has 20 owner complaints and 6 recall campaigns on record for the 2021 Ford E-350. The most complained-about area is engine.
Does the 2021 Ford E-350 have open recalls?
6 recall campaigns have been issued, the latest concerning engine. Check your specific vehicle by VIN - recall repairs are free at franchised dealers.
Source: NHTSA recall campaigns and owner complaints (public domain). Counts reflect reports on file and are not a defect rate.